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For example, one of the major goals ofoccupational medicine is to return the patient to work as quickly as is medically war-ranted. Note the population of Leydig (interstitial) cells that occur in small clusters in the spacebetween adjoining tubules

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Althoughpro-oxidant activity of p53 can be benecial for elimination of cancer cells, it mighthave some disadvantages for the organism under conditions of ischemia, neurodegen-eration or aging [102]; consequently tight p53 regulation is critical for proper controlof many physiological processes associated with p53 activation (Fig.